Drivers will face a 35-mile diversion as a road off the A14 will close for emergency works.
Newton Road in Stowmarket will be closed between 7pm on Friday and 5am on Saturday.
READ MORE: Man dies after medical emergency in town centre
A 35-mile diversion will be in place along the B1113, A140 and A143.
A spokesperson for Suffolk Highways said the road has been closed for urgent carriageway maintenance such as filling in potholes.
Comments: Our rules
We want our comments to be a lively and valuable part of our community - a place where readers can debate and engage with the most important local issues. The ability to comment on our stories is a privilege, not a right, however, and that privilege may be withdrawn if it is abused or misused.
Please report any comments that break our rules.
Read the rules here